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Torstein Tengs, Thomas LaFramboise, Robert B Den, David N Hayes, Jianhua Zhang, Saikat DebRoy, Robert C Gentleman, Keith O'Neill, Bruce Birren, and Matthew Meyerson (2004)
Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments.
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Nucleic Acids Res 32(15):e121.
We have developed a method for genomic representation using Type IIB restriction endonucleases. Representation by concatenation of restriction digests, or RECORD, is an approach to sample the fragments generated by cleavage with these enzymes. Here, we show that the RECORD libraries may be used for digital karyotyping and for pathogen identification by computational subtraction.
automatic medline import
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